Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Pneumothorax-II

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...

Cushing Syndrome II: Pathophysiology

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Early response toward clinical remission with dupilumab in severe asthma: Real-world cohort.

The journal of allergy and clinical immunology. Global·2026

Same author

Regional Variation in Home Oxygen Therapy Use in Japan: An Age-Standardized Ecological Analysis Using the NDB Open Data.

Geriatrics & gerontology international·2026

Same author

Esophageal Large-cell Neuroendocrine Carcinoma With Pagetoid Spread: A Case Report and Literature Review.

In vivo (Athens, Greece)·2026

Same author

Differential responses of group 2 innate lymphoid cells and T<sub>H</sub>2 cells to benralizumab in severe asthma.

The Journal of allergy and clinical immunology·2026

Same author

Immunostaining and Ciliary Movement Analysis in Primary Ciliary Dyskinesia With a Homozygous Deletion Involving Exons 1-4 of <i>DRC1</i>: A Case Report.

Respirology case reports·2026

Same author

Impact of varenicline supply suspension on smoking cessation services in Japan's universal health insurance system.

Respiratory investigation·2026

Search research articles

Related Experiment Video

Updated: Jul 15, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

Good Syndrome Presenting With Pulmonary Abnormalities Four Years After Thymectomy.

Tomohide Hanawa^1,2, Tomohiro Akaba¹, Yuka Kaizu³

¹Department of Respiratory Medicine Tokyo Women's Medical University Tokyo Japan.

Respirology Case Reports

|July 14, 2026

Summary

Good syndrome, a rare immunodeficiency linked to thymoma, can manifest years after thymectomy. Early diagnosis and treatment with immunoglobulin therapy are crucial for managing recurrent infections and improving outcomes.

Keywords:

good syndrome hypogammaglobulinemia recurrent infection thymoma

More Related Videos

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Related Experiment Videos

Last Updated: Jul 15, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Area of Science:

Immunology
Oncology
Pulmonology

Background:

Good syndrome is a rare primary immunodeficiency characterized by thymoma, hypogammaglobulinemia, and B-cell depletion.
Recurrent respiratory infections and unexplained pulmonary abnormalities can be presenting symptoms.

Purpose of the Study:

To highlight Good syndrome as a potential diagnosis in patients with a history of thymoma presenting with recurrent respiratory infections and pulmonary abnormalities.
To emphasize the importance of immunologic evaluation in diagnosing Good syndrome post-thymectomy.

Main Methods:

Case report of a 72-year-old woman with a history of thymectomy presenting with recurrent respiratory infections.
Diagnostic workup included chest CT, bronchoalveolar lavage, and comprehensive immunologic evaluation.
Treatment involved corticosteroids, antibiotics, and subsequent intravenous immunoglobulin therapy.

Main Results:

The patient was diagnosed with Good syndrome, exhibiting profound hypogammaglobulinemia and near absence of peripheral B cells.
Treatment with intravenous immunoglobulin led to increased serum IgG levels and prevention of further respiratory infections.
Pulmonary abnormalities and respiratory symptoms improved with treatment.

Conclusions:

Good syndrome can present clinically years after thymectomy, even without thymoma recurrence.
Prompt immunologic assessment and treatment are essential for managing Good syndrome and its complications.
This case underscores the need to consider Good syndrome in the differential diagnosis of post-thymectomy patients with respiratory issues.