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Updated: Jul 15, 2026

A Mini-Invasive Internal Fixation Technique for Studying Immobilization-Induced Knee Flexion Contracture in Rats

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Published on: May 20, 2019

Dynamic Versus Stable Fixation of Distal Tibiofibular Joint Injuries: A Meta-Analysis Comparing Functional Outcomes.

Leon Liu¹, Pradith Santapur¹, Taylor Checkley¹

¹Allopathic Medicine, Nova Southeastern University, Dr. Kiran C. Patel College of Allopathic Medicine, Fort Lauderdale, USA.

|July 14, 2026

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Dynamic fixation for syndesmotic injuries shows potential for better functional outcomes and less pain than static fixation. However, high heterogeneity limits definitive conclusions, requiring larger studies for guideline recommendations.

Area of Science:

Orthopaedic Surgery
Sports Medicine
Biomechanics

Background:

Syndesmotic injuries can lead to chronic instability, pain, and osteoarthritis.
Current management options include static screw fixation and dynamic suture button devices.
Dynamic fixation aims to preserve physiological joint micromotion, potentially improving outcomes.

Purpose of the Study:

To systematically review and meta-analyze randomized controlled trials comparing dynamic and static fixation for syndesmotic injuries.
To evaluate the impact of fixation method on functional outcomes and postoperative pain.
To assess the overall evidence quality and identify areas for future research.

Main Methods:

Systematic review and meta-analysis of prospective randomized controlled trials (RCTs) published in PubMed and Google Scholar (June 2025).

Keywords:

dynamic fixation dynamic single screw fixation stable fixation tibio-fibular joint injury tibio-fibular syndesmosis

Related Experiment Videos

Last Updated: Jul 15, 2026

A Mini-Invasive Internal Fixation Technique for Studying Immobilization-Induced Knee Flexion Contracture in Rats

A Mini-Invasive Internal Fixation Technique for Studying Immobilization-Induced Knee Flexion Contracture in Rats

Published on: May 20, 2019

Included 4 RCTs with 250 adult patients diagnosed with syndesmotic injuries.

Analyzed data using Covidence and RevMan 5.4.1, employing a random-effects model for pooled outcomes.

Main Results:

Dynamic fixation showed comparable American Orthopaedic Foot and Ankle Society (AOFAS) scores but significantly higher Olerud-Molander Ankle Scores (OMAS).
Patients undergoing dynamic fixation reported significantly lower Visual Analogue Scale (VAS) pain scores postoperatively.
Risk of bias was low to moderate, with incomplete blinding as a primary limitation.

Conclusions:

Dynamic fixation may offer superior functional outcomes and reduced pain compared to static screw fixation for syndesmotic injuries.
Significant heterogeneity in pooled estimates, especially for AOFAS scores (I² = 96%), reduces confidence in findings.
Larger RCTs with standardized protocols are necessary to establish definitive conclusions and inform clinical guidelines.