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Prospective Randomized Study of Visual Outcomes with Mini-Monovision Between the Light-Adjustable Lens and Clareon
Clayton Blehm1, Zach Balest1, Brad Hall2
1North Georgia Eye Associates, Gainesville, GA, USA.
Clinical Ophthalmology (Auckland, N.Z.)
|July 14, 2026
Summary
This study compared the Light-Adjustable Lens (LAL) and Clareon monofocal toric intraocular lenses for mini-monovision. Both lenses demonstrated comparable refractive and visual outcomes, with Clareon offering faster routine care release.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Intraocular Lens Technology
Background:
- Mini-monovision is a strategy to achieve spectacle independence.
- Comparing different intraocular lens (IOL) technologies is crucial for optimizing refractive outcomes.
- The Light-Adjustable Lens (LAL) and Clareon monofocal toric IOL are advanced options for cataract surgery.
Purpose of the Study:
- To compare binocular visual outcomes between the LAL and Clareon monofocal toric IOL.
- To evaluate refractive accuracy and spectacle independence in a mini-monovision setting.
- To assess the time to release of care after implantation of these IOLs.
Main Methods:
- A prospective, randomized, double-arm, multi-surgeon study.
- Evaluation of visual acuities (distance, intermediate, near) at 1 and 3 months postoperatively.
- Collection of data on higher order aberrations, spectacle independence, and refractive accuracy.
Main Results:
- Clareon was non-inferior to LAL for most binocular visual acuities at 3 months.
- Spectacle independence rates were high for both IOLs, with LAL showing slightly higher near independence.
- Routine care release was significantly faster for the Clareon group (31.7 days) compared to the LAL group (53.9 days).
Conclusions:
- Both Clareon monofocal toric and LAL IOLs provide good refractive and visual outcomes when targeting mini-monovision.
- Clareon offers a faster recovery and release of care compared to LAL.
- Further research may explore long-term visual stability and patient-reported outcomes.
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