Integrating implementation science to explore barriers and facilitators influencing nurses' bioterrorism...

Area of Science:

• Implementation Science
• Public Health
• Nursing Research

Background:

• Bioterrorism poses significant public health threats requiring robust emergency response.
• Nurses are essential in early detection, isolation, and care during bioterrorism events.
• Existing gaps in nursing bioterrorism preparedness necessitate a comprehensive synthesis of influencing factors.

Purpose of the Study:

• To systematically synthesize evidence on barriers and facilitators impacting nurses' bioterrorism preparedness.
• To utilize the Consolidated Framework for Implementation Research (CFIR 2.0) to guide the synthesis.
• To identify determinants influencing the implementation of bioterrorism preparedness among nurses.

Main Methods:

• Mixed-methods systematic review following Joanna Briggs Institute (JBI) and PRISMA-P guidelines.
• Comprehensive literature search across multiple databases (CINAHL, PubMed, Embase, etc.) until March 2026.
• Thematic mapping to CFIR 2.0 constructs and convergent integrated data synthesis using the Mixed Methods Appraisal Tool (MMAT).

Main Results:

• This review is expected to be the first implementation science synthesis of determinants for nurse bioterrorism preparedness.
• It will integrate evidence from diverse methodological traditions.
• Findings will illuminate individual, organizational, and contextual factors affecting preparedness.

Conclusions:

• This systematic review will provide a comprehensive understanding of factors influencing nurses' bioterrorism preparedness.
• Findings will inform evidence-based preparedness planning and nursing education.
• The review aims to strengthen healthcare system resilience to biological threats.