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Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
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Applying Machine Learning Models to Predict Occupational Noise-Induced Hearing Loss: A Systematic Review and

ZhongHao Wang1, YingYing Fan2, XueYan Zhang1

  • 1National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.

Noise & Health
|July 14, 2026
PubMed
Summary

Machine learning models show promise for predicting occupational noise-induced hearing loss (ONIHL). However, current evidence requires cautious interpretation due to high bias and heterogeneity in studies.

Keywords:
hearing lossmachine learningnoisepredictive modelsystematic review

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Area of Science:

  • Occupational health
  • Biomedical informatics
  • Machine learning applications

Background:

  • Occupational noise-induced hearing loss (ONIHL) is a significant public health concern.
  • Machine learning (ML) offers potential for developing predictive models for ONIHL.
  • Critical appraisal of existing ML models for ONIHL prediction is needed.

Purpose of the Study:

  • To systematically map and critically appraise ML-based prediction models for ONIHL.
  • To evaluate the reporting quality and risk of bias in these models.
  • To assess the performance of ML models in predicting ONIHL.

Main Methods:

  • Systematic literature search across seven databases.
  • Reporting quality assessed using TRIPOD-AI checklist.
  • Risk of bias and applicability evaluated using PROBAST tool.
  • Meta-analysis of ML model performance (AUC) with subgroup analyses.

Main Results:

  • Sixteen studies included, with Support Vector Machine (SVM), Random Forest, and Artificial Neural Network (ANN) as common algorithms.
  • Input variables often included age, noise level, and exposure duration, with limited consideration of noise type.
  • Meta-analysis showed a pooled AUC of 0.788 for ML models; XGBoost and ANN achieved the highest AUC (0.846).
  • Significant risk of bias (56%) and applicability concerns (31%) were identified.

Conclusions:

  • ML models show potential for ONIHL prediction.
  • High risk of bias, heterogeneity, and lack of external validation necessitate cautious interpretation of current findings.
  • Further well-designed studies are required to improve the reliability and applicability of ML models for ONIHL prediction.