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Published on: April 1, 2018
High-Intensity Virtual Reality Exergaming for Adolescents With Attention-Deficit/Hyperactivity Disorder: Protocol for
Martin Romero Meller1,2,3, Natália Balbinot Zanini2, Renato Keitel Machado2
1Graduate Program in Psychiatry and Behavioral Sciences, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
This study investigates if a virtual reality (VR) high-intensity interval training (HIIT) exergame improves attention and impulse control in adolescents with ADHD more than a non-exercise VR control. Results are pending, but the trial aims to determine if physical exertion in VR is key for ADHD symptom improvement.
Area of Science:
- Neuroscience
- Clinical Psychology
- Exercise Physiology
Background:
- Attention-deficit/hyperactivity disorder (ADHD) affects 7-8% of youth, with adolescence being a vulnerable period.
- Traditional ADHD treatments face challenges like adverse effects and poor adherence.
- Virtual reality (VR) exergames offer a novel approach to engage adolescents with ADHD in physical activity.
Purpose of the Study:
- To evaluate if a high-intensity interval training (HIIT)-based VR exergame improves inhibitory control and inattention in adolescents with ADHD.
- To compare the HIIT-VR exergame against an active, non-exercise VR control group.
- To determine the specific contribution of physical exertion in VR for ADHD symptom management.
Main Methods:
- A randomized clinical trial involving 98 adolescents (12-17 years) diagnosed with ADHD.
- Participants are allocated to either an HIIT-based VR exergame or an active VR control group.
- Primary outcomes include inattention symptoms (Swanson, Nolan, and Pelham Rating Scale) and go/no-go task performance.
Main Results:
- The trial is ongoing, with 58 participants enrolled and 46 completing the intervention as of April 2026.
- Data collection is expected to conclude by October 2026.
- Results are anticipated by December 2026.
Conclusions:
- This trial will provide controlled evidence on the efficacy of HIIT-based VR exergames for adolescents with ADHD.
- It will clarify if vigorous physical exertion, beyond VR immersion, is crucial for improving ADHD symptoms.
- The findings may support the development of engaging, home-based adjunctive treatments for ADHD.

