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Endoscopic Ipsilateral Posterior Interhemispheric Transprecuneus Approach for Central Neurocytoma.

Tengfei Liu¹, Chongjing Sun¹, Shuang Liu¹

¹Department of Neurosurgery, Zhongshan Hospital, Fudan University, Shanghai, China.

Operative Neurosurgery (Hagerstown, Md.)

|July 14, 2026

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The endoscopic ipsilateral posterior interhemispheric transprecuneus approach (IPITA) offers a safe and effective surgical option for central neurocytoma in the lateral ventricle. This minimally invasive technique achieved high resection rates and favorable outcomes in a recent study.

Area of Science:

Neurosurgery
Neuro-oncology
Minimally Invasive Surgery

Background:

Central neurocytoma treatment is complex due to rarity and location.
Optimal surgical strategies for lateral ventricle tumors require further investigation.

Purpose of the Study:

To evaluate the surgical technique and feasibility of the endoscopic ipsilateral posterior interhemispheric transprecuneus approach (IPITA).
To assess IPITA's efficacy in treating central neurocytoma within the lateral ventricle.

Main Methods:

Retrospective analysis of 12 patients with central neurocytoma treated via IPITA.
Data included clinical outcomes and follow-up after resection from July 2018 to July 2025.

Main Results:

Keywords:

Central neurocytoma Endoscopy Lateral ventricle Transprecuneus approach

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Total resection was achieved in 11 out of 12 patients; one patient had subtotal resection (STR).

Two patients developed postoperative hydrocephalus, managed with shunt or septostomy.

No recurrence was observed in 11 patients; one patient with STR recurred after 30 months and received radiotherapy.

Conclusions:

The endoscopic IPITA is a safe and effective approach for resecting lateral ventricle central neurocytoma.
This technique is particularly beneficial for tumors in the posterior lateral ventricle body or involving the trigone.