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Updated: Jul 16, 2026

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Published on: February 6, 2015

Safety and real-world outcomes from a home-based, systemic anticancer therapy program: A prospective observational

Borja Gomez-Mediavilla¹, Maria Lanza-Postigo², Carmen Hinojo Gonzalez³

¹Department of Nursing, Universidad de Cantabria, Santander, Spain; Nursing Research Group, IDIVAL - Health Research Institute Valdecilla, Santander, Spain; Research Group of Qualitative and Mixed Methods in Health Sciences (QMix Health), Department of Nursing, Universidad de Cantabria, Santander, Spain.

International Journal of Nursing Studies

|July 14, 2026

Summary

Home administration of systemic anticancer therapies is safe and feasible for oncology patients. This nurse-led program reduces hospital burden while maintaining treatment adherence and safety.

Keywords:

Antineoplastic agents Drug-related side effects and adverse reactions Home care services Hospital-based Neoplasms Patient safety

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Last Updated: Jul 16, 2026

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo

Published on: February 6, 2015

Area of Science:

Oncology
Healthcare Management
Nursing

Background:

Increasing patient numbers strain oncology day hospitals.
Frequent visits impact patient quality of life.
Home administration of therapies offers a solution.

Purpose of the Study:

Evaluate safety and feasibility of home-based systemic anticancer therapy administration.
Assess a nurse-led program for home oncology care.

Main Methods:

Prospective observational study.
Adult oncology patients receiving selected therapies.
Predefined clinical criteria for home administration.

Main Results:

186 patients, 2226 home administrations.
Zero infusion reactions, extravasations, or urgent complications.
Maintained adherence and hospital workflows.

Conclusions:

Home administration is feasible and safe with proper protocols.
Specialized nursing and patient selection are key.
Home-based programs optimize resources and ensure safe therapy delivery.