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Updated: Jul 16, 2026

Methods to Study Lipid Alterations in Neutrophils and the Subsequent Formation of Neutrophil Extracellular Traps
Published on: March 29, 2017
Lung lipids license neutrophils to grease the gate
Maxwell Bannister1, Mikala Egeblad2
1Medical Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Abstract:
Metabolic alterations and neutrophils define the pre-metastatic niche, but the mechanisms connecting them remain incompletely understood. In this issue of Immunity, Qian et al. show that endothelial-derived palmitate induces neutrophils to release lipocalin-2, disrupting vascular integrity and promoting lung metastasis.
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