Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 16, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

Concordance between MRI Findings and Targeted Biopsy for Local Recurrence Following Radical Prostatectomy.

Sean A Fletcher1, Brittney H Cotta2, Emily A Vertosick3

  • 1Department of Surgery (Urology Service), Memorial Sloan Kettering Cancer Center, New York, New York.

Urology
|July 14, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neoadjuvant intraprostatic immunotherapy for high-risk localized prostate cancer.

Nature reviews. Urology·2026
Same author

Cancer-specific mortality of grade group 1 prostate cancer: Results from Surveillance, Epidemiology, and End Results Database, 2004-2021.

Current urology·2026
Same author

Segmentation regularized training for multi-domain deep learning registration applied to magnetic resonance-guided prostate cancer radiotherapy.

Physics and imaging in radiation oncology·2026
Same author

ASO Visual Abstract: Identifying Predictors of Delayed Ambulation After Minimally Invasive Gynecologic Oncology Surgery.

Annals of surgical oncology·2026
Same author

Early outcomes of partial gland (focal) salvage brachytherapy for radiorecurrent prostate cancer.

Brachytherapy·2026
Same author

Identifying Predictors of Delayed Ambulation After Minimally Invasive Gynecologic Oncology Surgery.

Annals of surgical oncology·2026

Magnetic Resonance Imaging (MRI) helps detect prostate bed recurrences after prostatectomy (RP). High suspicion MRI lesions correlate with biopsy-confirmed cancer, guiding treatment decisions for salvage radiotherapy.

Area of Science:

  • Urology
  • Radiology
  • Oncology

Background:

  • Prostate cancer recurrence after radical prostatectomy (RP) can occur in the prostate bed.
  • Accurate detection of recurrent prostate cancer is crucial for effective treatment planning.

Purpose of the Study:

  • To evaluate biopsy outcomes for suspicious prostate bed lesions detected by MRI after RP.
  • To understand the correlation between MRI suspicion levels and biopsy-confirmed viable cancer.

Main Methods:

  • Patients with biochemical recurrence (BCR) after RP underwent MRI-targeted biopsy of suspected prostate bed lesions.
  • A 5-point index score graded MRI suspicion for recurrence.
  • Biopsy results served as the reference standard.

Main Results:

More Related Videos

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

Related Experiment Videos

Last Updated: Jul 16, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
06:08

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

Published on: March 21, 2025

  • 55% of targeted biopsies confirmed recurrent prostate cancer.
  • Higher MRI suspicion scores significantly correlated with positive biopsy results (p=0.003).
  • Androgen deprivation therapy prior to biopsy was associated with positive results (p=0.022).

Conclusions:

  • MRI is effective in detecting prostate bed recurrences.
  • High-suspicion MRI lesions are likely to be viable cancer on biopsy.
  • Confirmatory biopsy is recommended for suspected recurrences, especially for patients eligible for salvage radiotherapy.