Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Preventive Healthcare Services

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

Testing a Claim about Population Proportion

Testing a Claim about Population Proportion

A complete procedure for testing a claim about a population proportion is provided here.
There are two methods of testing a claim about a population proportion: (1) Using the sample proportion from the data where a binomial distribution is approximated to the normal distribution and (2) Using the binomial probabilities calculated from the data.
The first method uses normal distribution as an approximation to the binomial distribution. The requirements are as follows: sample size is large...

Disorders of the Male Reproductive System

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

Cancer Vaccines

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Corrigendum to "Robot-assisted Kidney Transplantation: The 8-year European experience" [Eur. Urol. 87(4) (2025) 468-475].

European urology·2026

Same author

Outcomes after kidney transplantation in patients with urinary diversions or bladder augmentations: A 20-year nationwide study.

Investigative and clinical urology·2026

Same author

IMPACT-Introduction of Mycotic Prophylaxis At Cystectomy Trial: perioperative mycotic prophylaxis with fluconazole to reduce postoperative complications following cystectomy-study protocol for a national multi-center, double-blinded, placebo-controlled, randomized clinical trial.

Trials·2026

Same author

Clinical Trial Protocol for ProBio-mHSPC: A ctDNA-driven De-escalation and Intensification Platform Trial for Metastatic Hormone-sensitive Prostate Cancer.

European urology focus·2026

Same author

Open Versus Robot-assisted Kidney Transplantation in Adults with End-stage Kidney Disease (ORAKTx): A Randomised Open-label Trial.

European urology·2026

Same author

Postoperative urinary tract infections and the role of Tc-99 m-MAG3 renography scans following construction of a urinary diversion.

International urology and nephrology·2026

Search research articles

Related Experiment Video

Updated: Jul 16, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

Prostate Cancer Screening: The Population Benefit Outweighs the Harm - Con.

Andreas Røder¹

¹Copenhagen Prostate Cancer Center, Department of Urology, Center for Cancer and Organ Diseases, Rigshospitalet, Copenhagen, Denmark.

European Urology Focus

|July 14, 2026

Summary

Prostate-specific antigen (PSA) screening offers a small survival advantage but leads to overdiagnosis and harm. This challenges its use as a widespread public health strategy.

Related Experiment Videos

Last Updated: Jul 16, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

Area of Science:

Urology
Oncology
Public Health

Background:

Prostate cancer screening using prostate-specific antigen (PSA) is a widely debated public health topic.
The balance between potential benefits and harms of PSA screening remains a critical area of research.

Purpose of the Study:

To evaluate the net benefit of PSA screening in the context of overdiagnosis and associated harms.
To critically assess the suitability of PSA screening as a population-level strategy.

Main Methods:

Review of existing literature on PSA screening efficacy and harms.
Analysis of data regarding mortality reduction versus overdiagnosis rates.

Main Results:

A modest mortality benefit was observed with PSA screening.
This benefit is intrinsically linked to significant rates of overdiagnosis and patient harm.

Conclusions:

The harms associated with overdiagnosis complicate the interpretation of PSA screening's benefits.
The role of PSA screening as a population strategy requires re-evaluation due to its complex risk-benefit profile.