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Related Concept Videos

Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...

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Computerized Adaptive Testing System of Functional Assessment of Stroke
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CT functional assessment: Why and how?

Yoshito Kadoya1

  • 1Division of Cardiology, Department of Medicine, University of British Columbia, Canada.

Journal of Cardiovascular Computed Tomography
|July 14, 2026
PubMed
Summary

Cardiac computed tomography (CT) offers valuable insights into heart function beyond coronary anatomy. Different CT strategies provide functional assessments, with full-cycle cine ejection fraction as the reference standard.

Keywords:
Cardiac CTCoronary CT angiographyEjection fractionRadiation doseVentricular function

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Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Diagnostics

Background:

  • Cardiac computed tomography (CT) primarily assesses coronary anatomy.
  • CT also provides clinically relevant data on ventricular and atrial size and function.
  • Optimal CT approach selection depends on clinical context, scanner capabilities, and heart rhythm.

Purpose of the Study:

  • To review practical strategies for cardiac CT functional assessment.
  • To discuss various CT acquisition methods for evaluating heart function.
  • To highlight the utility of CT in assessing ventricular and atrial size and function.

Main Methods:

  • Retrospective electrocardiogram (ECG)-gated cine CT.
  • Low-dose functional cine protocols.
  • Prospective ECG-triggered coronary CT angiography.
  • Recirculation-phase cine CT.

Main Results:

  • Prospective diastolic acquisitions yield mid-diastolic volume and mass indices.
  • Systolic acquisitions provide left ventricular ejection fraction over 100 ms of systole (LVEF100ms) as a surrogate marker.
  • These methods can extend cardiac CT value without extra radiation or contrast, even in atrial fibrillation.

Conclusions:

  • Cardiac CT functional assessment strategies vary based on clinical needs.
  • Full-cycle cine ejection fraction is the reference CT-derived measure.
  • Limited-phase and low-dose approaches are informative but not interchangeable; planning is crucial.