Related Experiment Video
Updated: Jul 16, 2026
11:07
Focal Laser Ablation of Prostate Cancer: An Office Procedure
Published on: March 30, 2021
Patient and Technology Selection for Focal Therapy in Prostate Cancer.
Mustafa Dinckal1, Rodrigo Rodrigues Pessoa2, Julio Pow-Sang2
1Department of Urology, Kars Harakani State Hospital, Kars 36200, Turkey.
Cancers
|July 15, 2026
Summary
Focal therapy offers organ preservation for localized prostate cancer, balancing cancer control with function. Careful patient selection, advanced imaging, and understanding tumor characteristics are key for successful outcomes.
Area of Science:
- Oncology
- Urology
- Medical Technology
Background:
- Focal therapy is an emerging organ-preserving treatment for localized prostate cancer.
- It aims to maintain urinary and sexual function alongside cancer control.
- Challenges include multifocal disease, imaging/biopsy limitations, and scarce long-term data.
Purpose of the Study:
- To review current evidence and consensus on focal therapy for prostate cancer.
- To guide oncological suitability, risk assessment, and patient/technology selection.
- To discuss the role of advanced imaging and treatment modalities.
Main Methods:
- Narrative review of existing literature and guidelines.
- Discussion of histopathological features, tumor burden, and imaging modalities.
- Analysis of anatomical factors, functional priorities, and follow-up protocols.
Main Results:
- Multiparametric MRI, PSMA PET, micro-ultrasound, and AI aid in planning.
- Tumor location and proximity to critical structures influence modality choice.
- Various ablative techniques (HIFU, cryotherapy, IRE, etc.) are discussed.
Conclusions:
- Focal therapy shows promise for selected prostate cancer patients.
- Careful patient selection, shared decision-making, and structured follow-up are crucial.
- Optimizing outcomes requires integrating imaging, pathology, and patient factors.
