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Treatment Modalities and Recurrence Outcomes in Odontogenic Keratocysts: A 24-Year Retrospective Analysis
Nur Efşan Aydın1, Özgür Dağal1, Nur Mollaoğlu1
1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gazi University, 06000 Ankara, Turkey.
Healthcare (Basel, Switzerland)
|July 15, 2026
Summary
Marsupialization showed lower recurrence rates for odontogenic keratocysts compared to enucleation. Careful treatment planning and long-term follow-up are crucial for managing these jaw cysts.
Area of Science:
- Oral and Maxillofacial Surgery
- Dental Pathology
- Oncology
Background:
- Odontogenic keratocysts are developmental jaw cysts, often asymptomatic until large.
- They commonly occur in the mandibular angle and ramus.
- High recurrence rates make optimal treatment controversial.
Purpose of the Study:
- To evaluate treatment modalities for odontogenic keratocysts.
- To identify treatments associated with lower recurrence rates.
Main Methods:
- Retrospective analysis of 291 odontogenic keratocyst cases (2000-2024).
- Evaluation of associations between patient demographics, lesion characteristics, treatment, and recurrence.
- Statistical analysis using SPSS v.27.
Main Results:
- Overall recurrence rate was 16.2%.
- Marsupialization had a 5% recurrence rate, enucleation 19.2%, and resection 0%.
- Treatment modality significantly impacted recurrence (p=0.014).
Conclusions:
- Treatment choice for odontogenic keratocysts requires careful consideration.
- Marsupialization may offer lower recurrence than enucleation in select cases.
- Long-term follow-up is essential due to potential late recurrences.