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A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
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Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
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Updated: Jul 16, 2026

Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue
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Published on: June 14, 2020

Paediatric Sleep-Disordered Breathing: Pharyngeal Airway and Lymphoid Tissues in Risk Assessment.

Sandra Yi Cheng Chee1, Lynn Huiting Koh2, Kelvin Weng Chiong Foong3

  • 1Department of Orthodontics, Faculty of Dentistry, National University of Singapore, 9 Lower Kent Ridge Rd, Singapore 119085, Singapore.

Journal of Clinical Medicine
|July 15, 2026
PubMed
Summary

Paediatric orthodontic patients in Singapore show high rates of adenotonsillar hypertrophy, a risk factor for sleep-disordered breathing (SDB). This study provides crucial cephalometric norms for identifying at-risk children needing SDB evaluation.

Keywords:
cephalometrycraniofacial abnormalitiesobstructive sleep apneaorthodonticssleep-disordered breathingupper airway

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07:31

Image Acquisition using Portable Sonography for Emergency Airway Management

Published on: September 28, 2022

Area of Science:

  • Orthodontics
  • Paediatric Dentistry
  • Sleep Medicine

Background:

  • Paediatric sleep-disordered breathing (SDB) is linked to upper airway constriction and craniofacial variations.
  • Population-specific cephalometric data are lacking for Asian children, hindering SDB risk assessment.
  • This study addresses the need for normative data in a Singaporean paediatric orthodontic cohort.

Purpose of the Study:

  • To investigate upper airway structure and lymphoid tissue hypertrophy in paediatric orthodontic patients.
  • To establish cephalometric dimensions for pharyngeal airway, skeletal, dental, and soft tissues.
  • To determine adenotonsillar hypertrophy prevalence and its association with demographic and skeletal factors.

Main Methods:

  • Retrospective analysis of lateral cephalograms from 404 children (aged 7-11 years) in Singapore.
  • Standardized cephalometric measurements assessed airway, skeletal, dental, and soft tissue parameters.
  • Comparisons made across demographic (age, gender, ancestry) and skeletal groups.

Main Results:

  • Significant differences in airway variables were observed based on gender, age, and skeletal patterns.
  • Adenotonsillar hypertrophy was prevalent (92.3%), with combined adenotonsillar hypertrophy in 49.5% and isolated tonsillar hypertrophy in 36.6%.
  • Younger, male, Chinese, Class I/II, and increased mandibular plane angle patients showed SDB anatomical risk indicators.

Conclusions:

  • Cephalometric norms for paediatric orthodontic patients in Singapore were established.
  • High prevalence of adenotonsillar and isolated tonsillar hypertrophy noted.
  • Population-specific data aid in identifying children potentially benefiting from SDB evaluation.