Postoperative Outcomes of Unroofing Technique for Anomalous Aortic Origin of a Coronary Artery With Intramural

Daichi Hosokawa1, Mika Saito1, Kanako Kishiki1

  • 1Department of Pediatric Cardiology, Sakakibara Heart Institute, Tokyo, JPN.

Cureus
|July 15, 2026
PubMed

Insights

Unroofing surgery for anomalous aortic origin of a coronary artery (AAOCA) shows good outcomes. A shorter preoperative distance between the aortic commissure and intramural coronary artery may predict postoperative aortic regurgitation.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Medical Imaging

Background:

  • Anomalous aortic origin of a coronary artery (AAOCA) with an intramural course can cause sudden cardiac death.
  • Unroofing is the standard surgical treatment for AAOCA.
  • Postoperative aortic regurgitation (AR) and its predictors after unroofing are not fully understood.

Purpose of the Study:

  • To evaluate the clinical outcomes of unroofing surgery for AAOCA with an intramural course.
  • To identify anatomical predictors of postoperative AR after unroofing.

Main Methods:

  • Retrospective analysis of 16 patients undergoing unroofing for AAOCA.
  • Preoperative CT measurement of commissure-intramural distance.
  • Evaluation of postoperative AR progression.

Main Results:

  • Median follow-up of six months with no deaths or reinterventions.
  • Postoperative AR progression occurred in 38% of patients (trivial to mild).
  • Shorter commissure-intramural distance correlated with AR progression (2.66 mm vs. 4.81 mm, p=0.047).

Conclusions:

  • Unroofing for AAOCA with intramural course offers favorable early outcomes.
  • A shorter preoperative commissure-intramural distance may predict postoperative AR.
  • Findings are exploratory due to small sample size.

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