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Intra- and inter-observer reliability of spinal inflection point localization: a cross-sectional radiographic study.
Guilherme Pianowski Pajanoti1, Altacílio Aparecido Nunes2, José Otávio Donadeli Tomé3
1Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Einstein (Sao Paulo, Brazil)
|July 15, 2026
Summary
Spinal inflection point localization on radiographs showed low reliability among less experienced observers. Standardized protocols or training are needed to improve accuracy in sagittal alignment analysis.
Area of Science:
- Orthopedics
- Radiology
- Biomechanical analysis
Background:
- Spinal inflection point localization is crucial for sagittal alignment analysis.
- Accurate localization impacts biomechanical interpretation and surgical planning.
- Reliability of this measurement by non-specialists is not well-established.
Purpose of the Study:
- To evaluate the intra- and inter-observer reliability of spinal inflection point identification.
- To assess the consistency of this measurement on lateral radiographs in asymptomatic adults.
- To determine the influence of evaluator experience on measurement reliability.
Main Methods:
- Cross-sectional study of 10 asymptomatic adults.
- Lateral and anteroposterior panoramic radiographs analyzed.
- Three orthopedic residents with <2 years experience localized inflection points using Surgimap® software.
- Measurements repeated across three sessions with 3-week intervals.
- Intra- and inter-observer agreement assessed using ICC and Cohen's kappa.
Main Results:
- Most common cervicothoracic inflection point: C7-T1; thoracolumbar: T12-L1.
- Low inter-observer agreement for cervicothoracic (kappa 0.19-0.41) and thoracolumbar (kappa -0.03-0.22) inflection points.
- Low intra-observer reproducibility (ICC 0.29-0.56 for both regions).
- Wide confidence intervals indicated low precision, potentially due to small sample size and evaluator inexperience.
Conclusions:
- Localization of spinal inflection points by non-specialist evaluators demonstrated low reliability.
- Significant variability in both intra- and inter-observer agreement was observed.
- Need for standardized protocols and enhanced training for accurate spinal inflection point identification.