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Explaining increased locoregional failure following TNT in RAPIDO

P J Nilsson1, I Prata2, M D Tanaka3

  • 1Department of Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden.

The British Journal of Surgery
|July 15, 2026
PubMed
Summary

No abstract available in PubMed .

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Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
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