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Published on: October 6, 2016
Musculoskeletal Pain in People Aging With HIV: A Global Narrative Review
Stacey M Cahoon1,2,3,4,5, Julie Bobitt1,2,3,4,5, Kathleen M Weber1,2,3,4,5
1Stacey M. Cahoon, PhD, is a Postdoctoral Fellow, Department of Anatomy & Cell Biology, Rush University Medical Center, Chicago, Illinois, USA.
Summary
Musculoskeletal (MSK) pain is common in aging people with HIV (PWH). More research is needed to understand HIV
Area of Science:
- Rheumatology
- Infectious Diseases
- Pain Management
Background:
- Musculoskeletal (MSK) pain is a prevalent, age-related condition.
- People with HIV (PWH) experience high rates of chronic pain, with MSK pain being the most common source and joints the most frequent site.
- As the PWH population ages, MSK pain presents a growing clinical and quality of life challenge.
Purpose of the Study:
- To review current knowledge on MSK pain in PWH.
- To identify critical knowledge gaps in understanding and managing MSK pain in this population.
Main Methods:
- Literature review of existing studies on MSK pain in PWH.
- Analysis of risk factors for MSK pain, considering their prevalence in PWH.
- Assessment of the limited comparative studies examining the effects of HIV and antiretroviral therapy (ART) on MSK pain.
Main Results:
- Established risk factors for MSK pain are frequently observed in PWH.
- Few studies specifically address MSK pain in PWH, and most lack adequate comparison groups.
- The direct impact of HIV and ART on MSK pain remains poorly understood.
Conclusions:
- MSK pain is a significant concern for aging PWH.
- Further research is essential to elucidate the role of HIV and ART in MSK pain.
- Understanding the interplay of biopsychosocial factors is crucial for developing effective pain management strategies.
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