Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in critically...
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
Dialysis01:27

Dialysis

Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Managing chronic kidney disease according to KDIGO risk categories: A primer for primary care.

Cleveland Clinic journal of medicine·2026
Same author

Misclassification of type 1 diabetes as type 2 diabetes in adults: practical guidance for screening and diagnosis for primary care providers.

Postgraduate medicine·2026
Same author

Updated Global Consensus Recommendations for Risk Stratification, Treatment Initiation, and Response Monitoring in Metabolic Dysfunction-Associated Steatotic Liver Disease.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2026
Same author

Clinical Care Pathway for the Risk Stratification and Management of Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease.

Gastroenterology·2026
Same author

A secondary data analysis on hypotheses generated by inexperienced clinical researchers: Cases from a randomized controlled study.

Health informatics journal·2025
Same author

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in People With Diabetes: The Need for Screening and Early Intervention. A Consensus Report of the American Diabetes Association.

Diabetes care·2025

Related Experiment Video

Updated: Jul 17, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Renal replacement therapy: current modalities, indications, and clinical considerations.

Laurena Dongmo Fotsing1, Jay H Shubrook1

  • 1Department of Clinical Sciences and Community Health, Touro University California, 1310 Club Dr., Bldg HR-83, Vallejo, CA 94592, United States.

Postgraduate Medical Journal
|July 15, 2026
PubMed
Summary

Chronic kidney disease (CKD) affects 10% globally. Early detection and understanding renal replacement therapy (RRT) options, including conservative management and innovative devices, are crucial for improving patient outcomes in end-stage kidney disease (ESKD).

Keywords:
CKDdialysisrenal replacement therapyrenal transplantation

Related Experiment Videos

Last Updated: Jul 17, 2026

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Area of Science:

  • Nephrology
  • Public Health

Background:

  • Chronic kidney disease (CKD) is a major global health concern, impacting approximately 10% of the world's population.
  • A significant majority of adults with CKD in the USA remain undiagnosed, leading to delayed treatment and progression to end-stage kidney disease (ESKD).

Purpose of the Study:

  • To review current renal replacement therapy (RRT) modalities for ESKD.
  • To highlight the significance of conservative management as a viable alternative.
  • To explore novel innovations in ESKD treatment.

Main Methods:

  • Literature review of existing RRT options.
  • Discussion of vascular access requirements for hemodialysis (HD) and peritoneal dialysis (PD).
  • Exploration of emerging technologies in kidney disease management.

Main Results:

  • RRT options for ESKD include hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation.
  • Conservative management is presented as an important alternative to RRT.
  • Wearable and portable HD devices represent promising innovations.

Conclusions:

  • Understanding and offering diverse RRT options, alongside conservative management, is vital for ESKD patients.
  • Emerging technologies like wearable HD devices hold potential to enhance patient quality of life.