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Published on: October 20, 2021
Temporary Phrenic Nerve Peripheral Nerve Stimulation for Intractable Hiccups: A Case Report.
Christopher Mallard1, Morgan Cowan1, Dalton House2
1University of Kentucky, Department of Anesthesiology, Lexington, KY.
Pain Medicine Case Reports
|July 15, 2026
Summary
Peripheral nerve stimulation (PNS) offers a new treatment for intractable hiccups (IH). This study shows phrenic nerve PNS significantly reduced hiccups in a patient refractory to other therapies, providing prolonged symptom relief.
Area of Science:
- Neurology
- Medical Devices
Background:
- Intractable hiccups (IH) lasting over a month cause significant morbidity.
- Standard therapies and interventions often fail for IH patients.
- Phrenic nerve peripheral nerve stimulation (PNS) targets the hiccup reflex arc.
