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Andes Virus - A Clinical Review
Gavin H Harris1,2, Anabel Sinchi3, James Lawler4
1Division of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, Emory University School of Medicine, Atlanta.
Abstract:
Andes virus (ANDV) is the sole orthohantavirus with documented human-to-human transmission. We summarize the epidemiology and clinical features of ANDV infection and review best practices in clinical management, as based on published expert consensus guidelines, field experience, and clinical trials. We also evaluate currently available and investigational treatments (including the use of antiviral agents), assess emerging monoclonal antibody therapies, and outline prospects for vaccine development. Finally, we discuss important infection prevention and control measures.
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