Related Experiment Video
Updated: Jul 17, 2026

12:18
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Annual wellness visits, cognitive function, and early dementia diagnosis
Elizabeth Kim1, Mukaila A Raji2, Efstathia Polychronopoulou3
1John Sealy School of Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Archives of Gerontology and Geriatrics
|July 15, 2026
Summary
Medicare Annual Wellness Visits (AWVs) are linked to earlier detection of mild cognitive impairment (MCI). This may help identify modifiable factors contributing to cognitive decline and dementia.
Area of Science:
- Gerontology
- Public Health
- Neurology
Background:
- Early dementia diagnosis is crucial for optimizing care and interventions.
- The impact of Medicare Annual Wellness Visits (AWVs) on mild cognitive impairment (MCI) detection rates is not well-understood.
Purpose of the Study:
- To investigate the association between AWVs and the timeliness of diagnosing MCI and Alzheimer's disease-related dementias (ADRD).
- To adjust for various confounding factors not previously accounted for in similar research.
Main Methods:
- Utilized Health and Retirement Study (HRS) data linked with Medicare claims (2011-2019).
- Created propensity score-matched cohorts comparing AWV and non-AWV participants.
- Employed Kaplan-Meier and Cox models to assess MCI/ADRD diagnosis risk within two years.
Main Results:
- The AWV group showed higher cognitive scores pre- and post-visit compared to the non-AWV group.
- MCI diagnoses were more frequent in the AWV cohort.
- Time to ADRD diagnosis was similar between groups, unaffected by behavioral or health determinant factors.
Conclusions:
- AWVs are associated with earlier detection of MCI.
- This earlier detection can inform patient-provider decisions regarding evaluations for modifiable factors impacting cognitive health.
Related Concept Videos
Dementia
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
The progression of dementia is generally gradual.
Dementia l: Introduction
Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Cognitive Development During Adulthood
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Alzheimer's Disease: Overview
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Alzheimer Disease l: Introduction
Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Alzheimer's Disease: Treatment
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
