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Updated: Jul 17, 2026

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
Published on: May 10, 2017
The Trigeminocardiac Reflex? Severe Bradycardia Secondary to Facial Trauma: A Case Report
Boris Penev1, Hallmon Hughes2, Katherine Scarpino1
1Medical University of South Carolina, Department of Emergency Medicine, Charleston, South Carolina.
Introduction:
The trigeminocardiac reflex (TCR), a physiologic response to irritation of the branches of the trigeminal nerve, was first described in humans in 1870. Gastric hypermotility, hypotension, bradycardia, and even asystole have been reported in response to surgical manipulation of the trigeminal nerve and its branches, but literature is limited in patients not undergoing surgery. Although effects are generally transient and benign, TCR can present a significant diagnostic and therapeutic challenge in patients undergoing surgical manipulation of the trigeminal nerve and its branches.
Case Report:
We describe a case of severe bradycardia secondary to facial trauma causing hemodynamic compromise and diagnostic uncertainty.
Conclusion:
This case highlights a possible case of TCR, as well as therapeutic considerations, in a patient presenting to the emergency department with severe facial trauma.
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