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Updated: Jul 17, 2026

Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain
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A Woman with Abdominal Pain.

Colton Conrad1, Reginald Alouidor2, Christopher Allison1,3

  • 1University of Massachusetts Medical School - TH Chan School of Medicine, Baystate Medical Center Department of Emergency Medicine, Springfield, Massachusetts.

Clinical Practice and Cases in Emergency Medicine
|July 15, 2026
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Summary

This case study highlights a rare instance of sigmoid colon intussusception in a young adult without a pathological lead point, potentially linked to chronic opioid use disorder and its effect on gut motility.

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Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Clinical Pathology

Background:

  • Sigmoid colon intussusception is typically associated with a pathological lead point.
  • Intussusception in young adults without a lead point is exceptionally uncommon.

Purpose of the Study:

  • To present a rare case of sigmoid colon intussusception in a young adult.
  • To explore potential etiologies for intussusception in the absence of a lead point.

Main Methods:

  • Case presentation of a 28-year-old woman with abdominal pain, nausea, vomiting, and constipation.
  • Diagnostic imaging including computed tomography (CT) of the abdomen and pelvis.
  • Surgical intervention and subsequent pathological examination of the resected specimen.

Main Results:

  • CT scan revealed sigmoid colon intussusception.
  • Surgical pathology confirmed intussusception with no identifiable pathological lead point.
  • Patient had a history of cocaine and opioid use disorder.

Conclusions:

  • Sigmoid intussusception in young adults without a lead point is rare.
  • Chronic opioid use disorder may contribute to decreased gut motility, potentially causing intussusception.
  • This case suggests a possible link between opioid use and idiopathic sigmoid intussusception.