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Updated: Jul 17, 2026

Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain
Published on: June 23, 2009
A Woman with Abdominal Pain
Colton Conrad1, Reginald Alouidor2, Christopher Allison1,3
1University of Massachusetts Medical School - TH Chan School of Medicine, Baystate Medical Center Department of Emergency Medicine, Springfield, Massachusetts.
This case study highlights a rare instance of sigmoid colon intussusception in a young adult without a pathological lead point, potentially linked to chronic opioid use disorder and its effect on gut motility.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Clinical Pathology
Background:
- Sigmoid colon intussusception is typically associated with a pathological lead point.
- Intussusception in young adults without a lead point is exceptionally uncommon.
Purpose of the Study:
- To present a rare case of sigmoid colon intussusception in a young adult.
- To explore potential etiologies for intussusception in the absence of a lead point.
Main Methods:
- Case presentation of a 28-year-old woman with abdominal pain, nausea, vomiting, and constipation.
- Diagnostic imaging including computed tomography (CT) of the abdomen and pelvis.
- Surgical intervention and subsequent pathological examination of the resected specimen.
Main Results:
- CT scan revealed sigmoid colon intussusception.
- Surgical pathology confirmed intussusception with no identifiable pathological lead point.
- Patient had a history of cocaine and opioid use disorder.
Conclusions:
- Sigmoid intussusception in young adults without a lead point is rare.
- Chronic opioid use disorder may contribute to decreased gut motility, potentially causing intussusception.
- This case suggests a possible link between opioid use and idiopathic sigmoid intussusception.
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