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Updated: Jul 17, 2026

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model
Published on: March 18, 2015
Programmable regenerative tissues: Converging mammalian synthetic biology and tissue engineering
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.
Abstract:
Synthetic biology can program cellular behavior but remains underused in regenerative medicine. This commentary argues that integrating synthetic biology with tissue engineering should target vascularization and immune integration through compact, context-aware circuits. Embedded within engineered tissues, these circuits could enable adaptive grafts that sense stress and coordinate regenerative responses.
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