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Related Concept Videos

Biological Effects of Radiation02:59

Biological Effects of Radiation

All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they produce ions...
Radiation: Applications01:17

Radiation: Applications

The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
Other Unique Bacteria01:18

Other Unique Bacteria

Magnetic bacteria exhibit a directed movement called magnetotaxis, driven by structures called magnetosomes. These magnetosomes consist of chains of magnetic particles made of either magnetite (Fe₃O₄) or greigite (Fe₃S₄) and are organized in a linear conformation by a protein scaffold within invaginations of the cell membrane. The bacteria align along the north–south magnetic field lines, much like a compass needle. They are typically microaerophilic or anaerobic and are commonly found near the...

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Related Experiment Video

Updated: Jul 17, 2026

An Automated Microscopic Scoring Method for the &#947;-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
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An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes

Published on: December 25, 2021

From Fragmentation to Integration: Building a Globally Harmonized Biodosimetry Framework for Radiological Emergency

Rajesh Kumar Chaurasia1, Arshad Khan1, Balvinder Kaur Sapra2

  • 1Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Mumbai, Mumbai, 400085, India.

Journal of Radiological Protection : Official Journal of the Society for Radiological Protection
|July 15, 2026
PubMed
Summary

Global radiation emergency preparedness requires enhanced biodosimetry. Establishing a global consortium with standardized protocols and shared platforms can significantly increase response capacity for mass-casualty radiological incidents.

Keywords:
Biodosimetry-NetworkDicentric and TriageRadiological-EmergencyRadiological-Management

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Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation
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Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation

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Irradiator Commissioning and Dosimetry for Assessment of LQ &alpha; and &beta; Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

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Last Updated: Jul 17, 2026

An Automated Microscopic Scoring Method for the &#947;-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
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An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes

Published on: December 25, 2021

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation
10:33

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation

Published on: September 4, 2017

Irradiator Commissioning and Dosimetry for Assessment of LQ &alpha; and &beta; Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

  • Radiation biology
  • Public health
  • International cooperation

Background:

  • Geopolitical instability and radiological/nuclear threats necessitate robust global radiation emergency preparedness.
  • Rapid biological dose assessment is critical for triage and health surveillance during radiation incidents.
  • Current biodosimetry methods, like the dicentric chromosome assay, face limitations in speed, throughput, and standardization for large-scale events.

Purpose of the Study:

  • To address the need for improved global biodosimetry capacity in radiological emergencies.
  • To advocate for a formally integrated global biodosimetry consortium.
  • To highlight the strategic imperative of harmonized biodosimetry for enhanced resilience.

Main Methods:

  • Review of existing biodosimetry techniques (dicentric assay, DNA-DSB foci, PCC-FISH).
  • Analysis of current global biodosimetry capacity, protocols, and infrastructure.
  • Modeling to assess the impact of coordinated laboratory activation.

Main Results:

  • Existing biodosimetry methods have limitations for mass-casualty scenarios.
  • Global biodosimetry capacity is fragmented with heterogeneous protocols and infrastructure.
  • Coordinated activation of laboratories could exponentially increase triage capacity.

Conclusions:

  • Isolated excellence in biodosimetry is insufficient for large-scale radiological emergencies.
  • A globally harmonized framework through a consortium is essential for scientific rigor and operational scalability.
  • Integration enhances collective resilience against unprecedented radiological threats.