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Multiscale Modeling of Embryonic Morphogenesis from Fertilization to Organogenesis
Debanik Deb1, Orishma Parida1, Laasya Naduthota1
1Theoretical and Computational Biology Lab, School of Biology, Indian Institute of Science Education and Research (IISER) Thiruvananthapuram, Thiruvananthapuram, Kerala, India.
None:
Embryonic development transforms a single cell into a structured multicellular organism through coordinated molecular, cellular, and tissue-level processes. In this review, we discuss multiscale modeling studies spanning early embryogenesis from fertilization to organogenesis across diverse systems, emphasizing how distinct computational frameworks have been used to investigate different stages of embryonic morphogenesis. Drawing on complementary animal models, we highlight how multiscale approaches provide mechanistic insights into embryonic patterning and form generation.
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