Implementation of resiliency interventions for caregivers of pediatric cancer patients: A systematic review

The purpose of this systematic review is to summarize what is known about the implementation of interventions targeting resiliency in caregivers of pediatric cancer patients to inform translation of effective strategies to the general population. Studies primarily conducted in North America evaluated various intervention strategies, predominantly delivered individually, to improve caregivers' coping skills, emotional well-being, and quality of life. Despite methodological diversity, including pilot and non-pilot designs, interventions generally reported positive impacts on psychosocial outcomes such as anxiety, depression, and resilience. Challenges identified include participant attrition, logistical barriers, and varying resource availability across study sites, highlighting implementation considerations for broader application. Recommendations include enhancing intervention specificity and addressing diversity gaps in participant demographics and intervention settings to optimize effectiveness and generalizability. Future research directions emphasize mechanistic pathways, implementation strategies, and adaptation frameworks to tailor interventions for diverse populations facing significant stressors beyond pediatric cancer caregiving.