Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vascularized Liver-on-a-Microsphere Reveals Alanine-Glucose Metabolism-Driven Regulation of Liver Function and Injury.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Diagnostic value of combined computed tomography lymphangiography and technetium-99m dextran lymphoscintigraphy in systemic lupus erythematosus complicated with chylous effusion and/or lymphedema.

Quantitative imaging in medicine and surgery·2026
Same author

Methods toward Single-Cell Total-Analysis.

Chemical reviews·2026
Same author

Flow-programmable and reversible surface-induced LLPS in nanofluidic channels.

Lab on a chip·2026
Same author

STOPOVER HOTSPOTS FOR MIGRATORY BIRDS IN NORTH AND CENTRAL AMERICA.

Biodiversity informatics·2026
Same author

β‑Ecdysone-Loaded Gelatin Methacryloyl Hydrogel Accelerates Diabetic Wound Healing by Improving Angiogenesis.

ACS omega·2026

Related Experiment Video

Updated: Jul 17, 2026

A Pipette-Tip Based Method for Seeding Cells to Droplet Microfluidic Platforms
06:50

A Pipette-Tip Based Method for Seeding Cells to Droplet Microfluidic Platforms

Published on: February 11, 2019

A One-Drop Quantitative Concentration Pipette Using Micro- to Centimeter-Scale Fluidics.

Ruying Wang1, Suyang Liu1, Xuan Yan1

  • 1Graduate School of Information, Production and Systems (IPS), Faculty of Science and Engineering, Waseda University, 2-7 Hibikino, Wakamatsu-Ku, Kitakyushu, Fukuoka 808-0135, Japan.

Analytical Chemistry
|July 16, 2026
PubMed
Summary

This study introduces a novel concentration pipette for microanalysis. It efficiently concentrates 1 mL samples to 10 μL with high recovery, overcoming challenges in handling small sample volumes.

More Related Videos

Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells
09:43

Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells

Published on: March 8, 2024

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets
08:20

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

Related Experiment Videos

Last Updated: Jul 17, 2026

A Pipette-Tip Based Method for Seeding Cells to Droplet Microfluidic Platforms
06:50

A Pipette-Tip Based Method for Seeding Cells to Droplet Microfluidic Platforms

Published on: February 11, 2019

Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells
09:43

Microfluidic Approach to Resolve Simultaneous and Sequential Cytokine Secretion of Individual Polyfunctional Cells

Published on: March 8, 2024

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets
08:20

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

Area of Science:

  • Analytical Chemistry
  • Microfluidics
  • Biotechnology

Background:

  • Microanalysis requires small sample volumes (10 μL), posing challenges in analyte integrity and recovery.
  • Existing methods like filtration and evaporation risk sample loss or complete evaporation.
  • Current cyclone evaporation techniques are unsuitable for microfluidic channels.

Purpose of the Study:

  • To develop a novel concentration pipette integrating concentration and sample ejection for microanalysis.
  • To address the challenge of sample loss and complete evaporation in microvolume sample preparation.
  • To provide an efficient and user-friendly solution for detecting small-volume samples.

Main Methods:

  • A multiscale fluidic device was constructed with centimeter, millimeter, and micrometer scales for distinct functions.
  • The device integrates cyclone concentration, sample stabilization in a single drop, and precise ejection.
  • The concentration pipette was designed to process 1.0 mL samples down to 10 μL at <30 °C.

Main Results:

  • The concentration pipette achieved nearly 100-fold concentration from 1.0 mL to 10 μL within 1.5 hours.
  • Maintained a high analyte recovery rate of over 95%.
  • Demonstrated applicability to large molecules (BSA), small molecules (Sunset Yellow), and atoms (Pb2+).

Conclusions:

  • The developed concentration pipette offers an economical, efficient, and user-friendly solution for microanalysis.
  • Effectively overcomes sample loss and ejection challenges in preparing small-volume samples.
  • Enables precise concentration and recovery of analytes for diverse detection platforms.