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Contemporary perspectives on metabolic surgery for type 2 diabetes: surgical techniques, outcomes, and complications

Jian Chen1, Wei Liu1, Yuxi Bai2

  • 1Department of General Surgery, Bethune International Peace Hospital, Shijiazhuang, Hebei, China.

Frontiers in Endocrinology
|July 16, 2026
PubMed

Insights

Metabolic surgery offers a key treatment for type 2 diabetes mellitus (T2DM) and obesity. This review details surgical options, efficacy, complications, and predictors for better diabetes management strategies.

Area of Science:

  • Endocrinology and Metabolic Diseases
  • Surgical Gastroenterology

Background:

  • Metabolic surgery is a significant therapeutic option for type 2 diabetes mellitus (T2DM) and obesity.
  • Clinical attention and research into surgical techniques and efficacy for T2DM management are increasing.
  • Concerns about diabetes recurrence and complications hinder widespread adoption in T2DM care.

Purpose of the Study:

  • To provide a systematic overview of metabolic surgical procedures for T2DM management.
  • To compare the efficacy and examine complications of various metabolic surgeries.
  • To evaluate preoperative predictors and long-term effectiveness of metabolic surgery for T2DM.

Main Methods:

  • Systematic review of current literature on metabolic surgery for T2DM.
  • Comparative analysis of surgical techniques, efficacy, and complication rates.
  • Evaluation of preoperative factors influencing surgical outcomes and long-term effectiveness.

Main Results:

  • The review synthesizes evidence on principal metabolic surgical procedures for T2DM.
  • Efficacy, complication incidence, and management strategies are compared across techniques.
  • Preoperative predictors and long-term outcomes of metabolic surgery are analyzed.

Conclusions:

  • Metabolic surgery is a viable option for T2DM and obesity management.
  • Understanding predictors and managing complications are crucial for routine application.
  • Evidence supports integrating metabolic surgery into multimodal diabetes care strategies.
Keywords:
diabetesdiabetes remissionefficacymetabolic mechanismsmetabolic surgerypostoperative complicationssurgical procedures

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