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Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
Multi-orientation non-confocal retinal imaging in an AOSLO using a Dove prism
Ruth E Woehlke1, Robert F Cooper1,2
1Joint Department of Biomedical Engineering, Marquette University and Medical College of Wisconsin, Milwaukee WI, 53226, USA.
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Adaptive optics scanning light ophthalmoscopes configured in a two-detector split-detection arrangement enable resolution of translucent retinal structures, producing phase contrast-based images of the retina's topography. Standard two-detector systems that use an edge mirror have reduced contrast for structures that lie perpendicular to the axis of the split mirror, reducing sensitivity and applicability of this technique. Here, rather than manipulating the axis of the split mirror (e.g. using a micromirror device), we rotate the light itself using a Dove prism and compare the approach to a two-detector configuration. We were able to resolve structures at multiple orientations in split-detection images using the Dove prism and combine them using a technique previously reported for four-detector devices.
