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Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders
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Parosmia Beyond Olfactory Loss: A Propensity Score-Matched Study of Central Sensitization-Associated Comorbidities

Elay Amidor1, Nidal Muhanna2, Avraham Abergel2

  • 1Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

International Forum of Allergy & Rhinology
|July 16, 2026
PubMed
Abstract

Keywords:
ParosmiaTriNetXcentral sensitizationfibromyalgiamigrainenociplastic painolfactory dysfunctiontinnitus

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Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...