Related Experiment Video

Updated: Aug 6, 2026

Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering
07:19

Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering

Published on: November 5, 2018

A critical appraisal of base-resolution m6A profiling techniques

Natalia Wawrzyniak1, Eduardo Eyras2, Justin J-L Wong3

  • 1Faculty of Bioscience Engineering, KU Leuven, Leuven 3000, Belgium; Epigenetics and RNA Biology Laboratory, Charles Perkins Centre, University of Sydney, Camperdown, New South Wales 2050, Australia; School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Camperdown, New South Wales 2050, Australia.

Trends in Biochemical Sciences
|July 16, 2026
PubMed

Keywords:
antibody-based approachesepitranscriptomicsm(6)A RNA modificationnanopore sequencingsingle-nucleotide RNA methylation mapping

More Related Videos

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline11:09

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline

Published on: January 5, 2017

Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling10:27

Contrast-Matching Detergent in Small-Angle Neutron Scattering Experiments for Membrane Protein Structural Analysis and Ab Initio Modeling

Published on: October 21, 2018

Related Concept Videos

Mass Analyzers: Overview01:13

Mass Analyzers: Overview

The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
¹H NMR: Complex Splitting01:13

¹H NMR: Complex Splitting

A proton M that is coupled to a proton X results in doublet signals for M. However, NMR-active nuclei can be simultaneously coupled to more than one nonequivalent nucleus. When M is coupled to a second proton A, such as in styrene oxide, each peak in the doublet is split into another doublet.
Splitting diagrams or splitting tree diagrams are routinely used to depict such complex couplings. While drawing splitting diagrams, the splitting with the larger coupling constant is usually applied first.