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Den-SOFA: Dental Student Outcome Forecasting Assistant using explainable machine learning models
Elnaz Shafigh1, Seyed Omidreza Mousavi2, Toktam Dehghani3
1Department of Operative Dentistry, Faculty of Dentistry, AJA University of Medical Sciences, Tehran, Iran.
BMC Medical Education
|July 17, 2026
Summary
Explainable machine learning (ML) models show promise in predicting dental student success on restorative dentistry exit exams, with academic factors being key predictors. Further validation is needed for practical application in student assessment.
Area of Science:
- Educational Data Mining
- Artificial Intelligence in Education
- Dental Education
Background:
- AI and ML are increasingly used in dental education for assessment and identifying at-risk students.
- Predictive modeling is challenging due to complex relationships between academic/demographic variables and student achievement.
- Interpretability is crucial for the value of predictive models.
Purpose of the Study:
- To evaluate Den-SOFA, an explainable ML framework, as a proof-of-concept for predicting outcomes on restorative dentistry exit examinations.
- To assess the predictive performance and interpretability of various ML models in dental education.
Main Methods:
- A descriptive-analytical educational data-mining study involving 96 dental students.
- Analysis of 26 academic and demographic variables.
- Evaluation of logistic regression, random forest, XGBoost, CatBoost, and artificial neural networks (ANN) for binary (pass/fail) and multiclass (grade A-F) predictions, using metrics like accuracy, F1-score, and AUC-ROC.
- SHAP analysis for model interpretability.
Main Results:
- ANN achieved the highest discrimination for pass/fail prediction (AUC-ROC=0.906).
- Random forest showed comparable performance with better interpretability.
- Multiclass grade prediction performance was moderate (best AUC-ROC=0.775).
- Academic term, cumulative GPA, phantom lab performance, and theoretical grades were key predictors; demographics had minimal impact.
Conclusions:
- Den-SOFA serves as an exploratory framework for applying explainable ML in dental education.
- Models demonstrated moderate-to-good internal predictive performance, especially for binary outcomes.
- External validation in diverse cohorts is necessary before operational use.