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Updated: Aug 6, 2026

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Advanced Olfactory Cancer Detection: When E-Noses Sniff the Skin

Liam Critchley

    Journal of Medical Internet Research
    |July 17, 2026
    PubMed
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    Olfaction01:25

    Olfaction

    The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
    The olfactory receptors are embedded in the cilia of the...
    Keywords:
    artificial intelligenceautomatedbiomarkersbiosensing techniquesbreath testsearly detection of cancerneoplasmspattern recognitiontumorvolatile organic compounds