Central Serous Chorioretinopathy in Kidney Transplant Recipients: A Report of Three Cases

Central serous chorioretinopathy (CSCR) is a retinal disorder characterized by subretinal fluid accumulation in the macular region and is commonly associated with psychological stress and prolonged corticosteroid exposure. In kidney transplant recipients, CSCR represents an underrecognized complication related to immunosuppressive therapy. We report three cases of CSCR occurring in male kidney transplant recipients receiving corticosteroid-based immunosuppression. Clinical presentation was dominated by decreased visual acuity and blurred vision. Diagnosis was established by ophthalmologic examination and fluorescein angiography in all cases, with optical coherence tomography (OCT) findings available in two patients. Two patients, aged 35 and 37 years, developed CSCR within weeks following transplantation while receiving corticosteroids, mycophenolate mofetil, and calcineurin inhibitors. In the third case, a 65-year-old diabetic patient was diagnosed incidentally during routine ophthalmologic follow-up. Gradual tapering of corticosteroids resulted in favorable clinical and visual outcomes in all patients. CSCR in kidney transplant recipients is mainly associated with prolonged corticosteroid therapy and may occur from the early post-transplant period to several years after transplantation. Early diagnosis and close collaboration between nephrologists and ophthalmologists are essential to optimize management, prevent visual complications, and preserve patients' quality of life.