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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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Benchmarking AI Protein Structure Predictors Reveals a Persistent Bias in Multi-State Proteins

Muhui Ye1, Yu-Hong Wang2, Maximilian Brogi1

  • 1School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.

Biorxiv : the Preprint Server for Biology
|July 17, 2026
PubMed

Keywords:
benchmarkingconformational ensemblesligand conditioningprotein structure prediction

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