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Updated: Aug 6, 2026

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan
Published on: June 29, 2018
Interactive online tool to identify genes associated with longevity in a panel of long-lived genetic mutants in C.
John N Hutchinson1,2, Jiaxi Guan3,4,5, Grant F Booth3,4,5
1Diamond Age Data Science, Somerville, Massachusetts, USA.
Abstract:
We recently used RNA sequencing to identify differentially expressed genes in a panel of nine long-lived mutants in C. elegans representing multiple different pathways of lifespan extension. In order make this data accessible to the research community, we have developed an online tool that allows users to examine the expression of a gene of interest in individual long-lived mutants or across all nine long-lived mutants. This tool will enable users to gain insight into how their genes of interest are modulated in long-lived genetic mutants and the extent to which expression of that gene is correlated with long life.

