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Racial and Gender-Based Disparities in Opioid Administration for Ocular Trauma
Hassaam S Choudhry1, David Mothy1, Aneesh Reddy2
1Department of Ophthalmology & Visual Science, Rutgers New Jersey Medical School, Newark, NJ, USA.
Ophthalmic Epidemiology
|July 17, 2026
Summary
Racial and gender disparities affect prehospital opioid administration for open globe injuries (OGIs). Non-White patients and females received fewer opioids, highlighting inequities in pain management for ocular trauma.
Area of Science:
- Emergency Medicine
- Ophthalmology
- Health Equity
Background:
- Opioid administration for pain management in prehospital settings is common.
- Open globe injuries (OGIs) are severe ocular emergencies requiring prompt pain relief.
- Social determinants of health (SDOH) may influence treatment disparities.
Purpose of the Study:
- To investigate how race and other SDOH impact prehospital opioid use for OGIs in the US.
- To identify factors associated with opioid administration in OGI cases.
- To analyze potential disparities in pain management for ocular trauma.
Main Methods:
- Analysis of National Emergency Medical Services Information System (NEMSIS) data (2017-2021).
- Inclusion of emergency medical service activations for OGIs, excluding cancellations and non-contact cases.
- Multivariate logistic regression adjusted for pain scores to determine factors influencing opioid administration.
Main Results:
- Among 53,589 OGI cases, females (OR 0.71) and non-White patients (African Americans OR 0.37; Hispanics OR 0.83) were less likely to receive opioids.
- Urban patients (OR 0.63) and those in the Midwest (OR 0.75), Northeast (OR 0.24), and South (OR 0.77) received fewer opioids compared to suburban and Western regions.
- Emergent cases (OR 1.85) and older adults (66-75 years, OR 1.41) were more likely to receive opioids.
Conclusions:
- Significant racial, regional, and gender disparities exist in prehospital opioid administration for OGIs.
- Addressing implicit bias and diversifying the EMS workforce are crucial.
- Clearer guidelines are needed to ensure equitable pain management for ocular trauma patients.
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