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Agentic AI-Assisted Coding Offers a Unique Opportunity to Instill Epistemic Grounding during Software Development

Magnus Palmblad1, Jared M Ragland2, Benjamin A Neely2

  • 1Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden2300 RC, Netherlands.

Journal of Proteome Research
|July 17, 2026
PubMed
Summary

AI-assisted coding is advancing rapidly. GROUNDING.md, a new document type, uses Hard Constraints and Convention Parameters to ensure scientific software correctness and democratize development.

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