Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pathological changes in virus enteritis of mink.

H A Reynolds

    Canadian Journal of Comparative Medicine : Revue Canadienne De Medecine Comparee
    |April 1, 1970
    PubMed
    Summary

    Viral enteritis of mink (VEM) causes significant lesions in the intestines, spleen, and lymph nodes. Early detection of nuclear inclusion bodies in mink is crucial for diagnosing VEM.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Three-dimensional NMR microscopy of rat spleen and liver.

    Magnetic resonance in medicine·1993
    Same author

    A scientific basis for proposed quality assurance of a new screening method for tumor-like growths in the planarian, Dugesia dorotocephala.

    Quality assurance (San Diego, Calif.)·1992
    Same author

    Cocarcinogenesis between cadmium and Aroclor 1254 in planarians is enhanced by inhibition of glutathione synthesis.

    Quality assurance (San Diego, Calif.)·1991
    Same author

    Performance of a multi-sector ultrasound hyperthermia applicator and control system: in vivo studies.

    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·1990
    Same author

    Phase II evaluation of doxorubicin for treatment of various canine neoplasms.

    Journal of the American Veterinary Medical Association·1989
    Same author

    Acute and short-term toxicoses associated with the administration of doxorubicin to dogs with malignant tumors.

    Journal of the American Veterinary Medical Association·1989

    Area of Science:

    • Veterinary Pathology
    • Virology
    • Animal Disease Research

    Background:

    • Viral enteritis of mink (VEM) is a significant disease affecting mink populations.
    • Understanding the pathogenesis of VEM is crucial for developing effective control strategies.

    Purpose of the Study:

    • To characterize the gross and histopathological lesions associated with viral enteritis of mink (VEM).
    • To determine the timeline of lesion development and the diagnostic significance of nuclear inclusion bodies.

    Main Methods:

    • Twenty-six, ten-week-old mink were experimentally infected with a Wisconsin strain of mink enteritis virus.
    • Animals were randomly selected daily for necropsy from post-inoculation day (PID) 4 through 13 to observe gross and histopathological changes.
    • Tissue samples were examined for lesions, including enteritis, splenic and lymph node alterations, and the presence of nuclear inclusion bodies.

    Main Results:

    • Macroscopic lesions such as fibrinous enteritis, splenic enlargement/hemorrhage, and lymph node edema were most prominent on PID 7 and 8.
    • Histopathological findings included intestinal epithelial necrosis, lymphocyte depletion in lymphoid organs, and myeloid/erythroid cell loss by PID 7 and 8.
    • Nuclear inclusion bodies, indicative of the causative agent, were most prevalent on PID 3, 4, and 5 in various tissues.

    Conclusions:

    • The study delineates the characteristic lesions and pathogenesis of VEM in experimentally infected mink.
    • Nuclear inclusion bodies are valuable diagnostic markers for early VEM detection, appearing before the peak of gross and histopathological lesions.

    Related Experiment Videos