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Use of Electromagnetic Navigational Transthoracic Needle Aspiration (E-TTNA) for Sampling of Lung Nodules
Published on: May 23, 2015
Pulmonary cryptococcosis showing a solitary nodule in patients with previous malignancy
1Department of Thoracic Surgery, Toho University Sakura Medical Center, Shimoshizu 564-1, Sakura, 285-8741, Chiba, Japan.
Abstract:
Pulmonary cryptococcosis is one of the pulmonary fungal infections caused by the inhalation of Cryptococcus neoformans. Pulmonary cryptococcosis shows various radiological findings and sometimes a pulmonary nodule on CT. We experienced three cases of pulmonary cryptococcosis showing a solitary nodule in patients with previous malignancy. All three cases show a newly emerging or growing nodule. Two cases whom FDG-PET was tested showed accumulation of FDG. All three cases underwent pulmonary resection and were pathologically diagnosed with pulmonary cryptococcosis. It is difficult to distinguish a pulmonary nodule due to cryptococcosis from pulmonary malignancy such as a primary lung cancer and a pulmonary metastasis. Especially, it is important to distinguish a pulmonary metastasis from a nodule due to infection in patients with previous malignancy. Surgical resection for diagnosis is often necessary for such cases.
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