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Updated: Aug 6, 2026
Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Midterm Outcomes of Neo-Modified Cabrol Coronary Reconstruction in Root-Involved Type A Aortic Dissection: A
Sen Yang1, Yun-Feng Zi1, Lei Pu1
1Department of Cardiovascular Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China; Key Laboratory of Cardiovascular Disease of Yunnan Province, Cardiovascular System Disease Clinical Medical Research Center of Yunnan Province, Clinical Medicine Center for Cardiovascular Disease of Yunnan Province, Kunming, Yunnan, China.
Background:
In Stanford type A aortic dissection with root involvement, coronary reconstruction determines perioperative safety and long-term perfusion. Outcomes of neo-modified Cabrol were evaluated in root-involved type A aortic dissection, with original Bentall serving as a contemporary reference.
Methods:
A retrospective single-center cohort (December 2012-June 2023) of 398 consecutive patients (neo-modified Cabrol, 349; original Bentall, 49) was analyzed. Baseline balance was improved by propensity scores with overlap weighting. The primary end point was 30-day all-cause mortality. Secondary end points included overall survival, computed tomography angiography-defined stenosis or occlusion of coronary interposition grafts, and major adverse valve-related events.
Results:
Thirty-day mortality was 7.2% (25/349) with neo-modified Cabrol and 8.2% (4/49) with original Bentall. Major perioperative complications did not differ significantly. Reverse Kaplan-Meier median follow-up was 4.23 years (3.55-5.85 years) for neo-modified Cabrol and 11.48 years (7.55-11.48 years) for original Bentall. Survival at 1 year, 5 years, and 10 years was 89.4%, 85.7%, and 82.5% for neo-modified Cabrol and 87.8%, 81.2%, and 73.7% for original Bentall. In a 30-day landmark overlap-weighted Cox model, late mortality hazard ratio was 0.69 (95% CI, 0.26-1.79); P = .442. Clinical follow-up of 30-day survivors was 100%. Graft-related events were rare (Gray P = .521); 2 cases of anastomotic stenosis occurred in the neo-modified Cabrol group, 1 moderate right coronary ostial and 1 severe left coronary ostial.
Conclusions:
Neo-modified Cabrol showed favorable perioperative and midterm outcomes in type A aortic dissection with root involvement.
