Related Experiment Video
Updated: Aug 6, 2026
A Porcine Model of Acute Respiratory Failure with a Continuous Infusion of Oleic Acid
Published on: March 8, 2024
Assessment of respiratory rate-oxygenation index (ROX), HACOR score and the C-reactive protein for prediction of
Aya Saber Sayed1, Eglal Hassan Elawady1, Sarah Ahmed Elmorsy1
1Department of Forensic Medicine and Clinical toxicology, Faculty of Medicine, Ain Shams University, Cairo, Egypt, Abbaseya, Cairo, Egypt.
Background:
Acute respiratory toxicity is a common presenting emergency in acutely poisoned patients. Unpredictable respiratory deterioration can occur regardless of the on-admission patients' stable state, leading to increased morbidity and mortality. This study aimed to evaluate the respiratory rate-oxygenation (ROX) index, heart rate, acidosis, consciousness, oxygenation and respiratory rate (HACOR) score and C-reactive protein (CRP) as predictors of mechanical ventilation (MV) in poisoned patients.
Methods:
This prospective study was conducted on poisoned patients with acute respiratory failure presented to the Poison Control Center-Ain Shams University Hospitals (PCC-ASUHs). Upon admission, all patients had their ROX index, HACOR score and CRP level measured at the time of admission and at 24 hours.
Results:
Seventy-two patients were enrolled in the study, where forty-one cases were mechanically ventilated. The initial ROX index was significantly lower in the mechanically ventilated group with a cut-off ≤ 18.85 at AUC (0.74). The 24-hour ROX index, HACOR score and CRP level were predictors of mechanical ventilation need at AUC (0.97, 0.94, 0.85, respectively).
Conclusion:
It was concluded from this study that the initial and 24-hour ROX index, 24-hour HACOR and CRP level can be predictors of MV in poisoned patients.
More Related Videos
14:28Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care
Published on: May 10, 2024
07:15Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Related Concept Videos
01:20Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
01:23Acute Respiratory Failure-IV
01:19Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
01:19Special considerations while measuring oxygen saturation
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is important.
01:23Assessment of Respiration
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like asthma or COPD,...
01:21Acute Respiratory Failure-I
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...