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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
Healthcare utilization patterns prior to a first heart failure diagnosis in a 90 day mortality cohort: A
Ellinore Nilsson1, Louise Pettersson2,3, Björn Agvall2,4
1Halland Hospital Halmstad, Region Halland, Halmstad, Sweden.
Background:
Early recognition of emerging heart failure prior to diagnosis could offer an opportunity for prevention-focused care, but it remains unclear whether healthcare seeking patterns before diagnosis indicate an earlier window for intervention. The objective was to determine if changes in utilization appeared during the 12-week pre-diagnosis period preceding a first diagnosis of heart failure with poor short-term prognosis.
Methods:
A retrospective population-based study in Region Halland, Sweden, used the Regional Healthcare Information Platform to identify persons aged 40-90 years with incident heart failure during 2013 to 2019 who had died within 90 days. Encounters across inpatient and outpatient care settings, estimated glomerular filtration rate, N-terminal pro B type natriuretic peptide (NT-proBNP), echocardiography status and comorbidities were retrieved. Repeated measures analysis assessed trends in weekly visits during the 12-week lookback, with covariance analysis adjusted for age, sex, hypertension, ischemic heart disease and diabetes.
Results:
The cohort included 902 individuals, mean age 85 years, 52% women. Echocardiography was not registered in 65%. Mean NT-proBNP measured 11,210 ng/L. The total average number of visits per week increased from 0.42 at week minus 12 to 1.77 at week 0 (p < 0.001). Primary care visits had increased from 0.30 to 0.72 (p < 0.001). Adjustments did not alter the pattern. No consistent early rise in visits appeared before the final two weeks.
Conclusions:
In this high-mortality population, healthcare utilization remained low and unchanged until a sharp rise immediately before diagnosis, indicating a narrow and late window for preventive action, which limits the feasibility of preventive intervention in routine care.
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