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Updated: Aug 6, 2026

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A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
Published on: October 2, 2012
Polyhydroxyalkanoate Synthase Mutant Derived from Bacillus cereus YB-4, Which Synthesizes Lower Molecular-Weight
Manami Ishii-Hyakutake1, Unurbat Uranbileg1, Yuki Miyahara1
1Department of Materials Science and Engineering, Institute of Science Tokyo, 4259 Nagatsuta, Midori-ku, Yokohama 226-8501, Japan.
Bioscience, Biotechnology, and Biochemistry
|July 20, 2026
Abstract
None:
Polyhydroxyalkanoate (PHA) synthase (PhaRCYB4) from Bacillus cereus YB-4 is a useful enzyme that produces PHA with various molecular weights depending on the host. The PhaRCYB4 mutant with an amino acid replacement of alanine at position 77 with serine in the PhaCYB4 subunit, which synthesized low-molecular-weight PHA, exhibited 2-fold higher polymerization activity than that of the wild-type enzyme.
