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Draft genome of Proteus mirabilis strain UACOMP-J6 isolated from the human endometrium

Nicole R Jimenez1, Melissa M Herbst-Kralovetz1,2

  • 1Department of Obstetrics and Gynecology, The University of Arizona College of Medicine-Phoenix, Phoenix, Arizona, USA.

Microbiology Resource Announcements
|July 20, 2026
PubMed

Insights

Researchers sequenced the genome of Proteus mirabilis UACOMP-J6, an endometrial bacterium. Its genome size and coding sequences were similar to other P. mirabilis strains from different environments.

Area of Science:

  • Microbiology
  • Genomics
  • Human Health

Background:

  • Proteus mirabilis is a bacterium found in various environments.
  • Endometrial hyperplasia is a condition affecting the uterine lining.

Purpose of the Study:

  • To sequence and annotate the genome of Proteus mirabilis UACOMP-J6.
  • To characterize the genomic features of this human endometrial isolate.

Main Methods:

  • Whole-genome sequencing of Proteus mirabilis UACOMP-J6.
  • Bioinformatic analysis for genome annotation and feature identification.

Main Results:

  • The genome size of UACOMP-J6 is 4.1 Mb with 38.8% GC content.
  • 3,774 coding sequences were identified in the UACOMP-J6 genome.
  • Genomic characteristics were comparable to P. mirabilis from other ecological niches.

Conclusions:

  • The genome of Proteus mirabilis UACOMP-J6 provides insights into its genetic makeup.
  • This study contributes to understanding the diversity of P. mirabilis in human-associated environments.
Keywords:
Proteus mirabilisendometriumgynecologyhyperplasiapathogensurinary tract infection

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