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A multitarget ruthenium-clotrimazole complex eradicates MRSA through membrane disruption, DNA intercalation, and ROS

Xiaoyin Wu1, Jinhao Li1, Wentao Lei1

  • 1Key Laboratory for Biobased Materials and Energy of Ministry of Education, College of Materials and Chemical Engineering, South China Agricultural University, Guangzhou 510642, China.

Bioorganic Chemistry
|July 20, 2026
PubMed

Keywords:
Antibiotic resistanceAntimicrobialBiofilm eradicationMembrane disruptionMultitarget mechanismRuthenium complex

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